ABSTRACT
Objective: Was present a general overview of the current treatments for HCV infection in adults.
Methods: A review study was conducted, Databases such as PubMed, MEDLINE and Scopus were used as information sources to identify and analyze the current information about the treatment for HCV infection in adults
Results: To define a treatment with the best likelihood of success, it is important to identify in each patient, their response predictors such as genotype and viral load as vital determinants. In addition, to age, male gender, prolonged infection, cirrhosis, hepatic fibrosis, elevated plasma ferritin, obesity, insulin resistance, African American and Hispanic ancestry and co-infection with HIV). Recently, it has been approved that the other drugs with direct antiviral activity (DAAs), like the protease inhibitors (Boceprevir and Telaprevir), inhibitors of the polymerase NS5B (deleobuvir and setrobuvir), inhibitors of replication complex NS5A, include daclatasvir, ledipasvir and cyclophilin inhibitors were introduced into clinical practice but this use is subject to the purchasing power of health institutions
Conclusion: To define a treatment with the best likelihood of success, it is important to identify in each patient, their response predictors such as genotype and viral load as vital determinants.
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.
Our 7 faculties and 12 professional schools offer more than 200 programmes to some 18,000 graduate, undergraduate and continuing studies students.
The UWI, Mona ranks first in Jamaica among accredited tertiary-level programmes. In 2012, the University was again one of Jamaica’s Top 100 Employers.
