C32J [CHEM3201] ORGANIC SYNTHESIS, BIOMOLECULES AND STEREOCHEMISTRY
(4 Credits) Semester 2 Level III

Pre-requisites: C22J (Pass or Fail but not Fail Absent)

Syllabus:

Target oriented organic synthesis. An introduction to retrosynthetic analysis. Reagents and methods for effecting carbon-carbon single and double bond formation, oxidation, reduction and cyclization. Mechanisms of carbo-cation and related rearrangements, substitution and elimination reactions. Stereochemistry of organic molecules. Static and dynamic aspects. The chemistry of carbohydrates- the synthesis and properties of mono- and disaccharides. The chemistry of amino acids, peptides and proteins.

A practical course of 36 hours.

Evaluation:

One 2-hour written paper 60%

In course test 20%

Practical Work 20%

Practical work is assessed throughout the duration of the course. Students whose practical work is considered to be unsatisfactory are required to sit a practical examination of not more than six hours duration. Candidates must provide the ORIGINAL notebooks of their laboratory work at the practical examination. These must be certified by the laboratory course Supervisor and may be taken into consideration by the Examiners.