The Jackson research group

Research Supervisors
Prof. Yvette Jackson
(B.Sc. (Special), Ph.D., UWI) Professor of Synthetic Organic Chemistry and Pro-Vice-Chancellor (Graduate Studies)
Dr. Nadale Downer-Riley
(B.Sc., Ph.D., UWI) Lecturer in Chemistry

 Current Students in Group

  • Flemoi Gordon
  • Alexa Redway
  • Sharna-kay Daley

Names of graduates from the group

  • Oscene Barrett (Ph.D., 2012Roxanne Higgins (M.Phil., 2011)
  • Andrew Morris (Ph.D., 2010)
  • Julie-Ann Grant (Ph.D., 2008)
  • Nadale Downer-Riley (Ph.D., 2007)
  • Seon Hepburn (Ph.D., 2004)
  • Norman Townsend (Ph.D., 2003)
  • Mario Anderson (Ph.D., 2002)
  • Karla-Sue Marriot (Ph.D., 2001)
  • Michael Lyon (Ph.D., 1998)
  • Gregory Simpson (Ph.D., 1996)
  • Mark Williams (M.Phil., 1996)
  • Ian Thompson (Ph.D., 1993)
  • Sharon Jones (M.Phil., 1992)

Research interests:
    Exploring new methodologies and mechanisms for the synthesis of heterocyclic compounds.
    The synthesis of and chemistry of bioactive heterocyclic compounds and their analogues.
 Target compounds:

  •    rotenoids (insecticidal compounds) – and their analogues
  •    diazepam (valium) - synthesis and study of the pharmacological activity of analogous salts
  •   marine alkaloids, eg. kuanoniamine A and violatinctamine -  synthesis of analogues

 

Recent Publications

  •    N. O. Townsend and Y. A. Jackson, Synthesis of 9-methyl-1H-[1,4]thiazino-[3,2-g]quinoline-2,5,10-(3H)-trione, the B,C,D ring core of the shermilamine alkaloids, Organic and Biomolecular Chemistry, 2003, 1, 3557-3563.
  •    N. K. Downer and Y. A. Jackson, Synthesis of Benzothiazoles via Ipso-Substitution of ortho-Methoxythiobenzamides, Organic and Biomolecular Chemistry, 2004, 2, 3039-3043 (cover article).
  •    Y. A. Jackson and S. A. Hepburn, A Concise Synthesis of Further Thiophene Analogues of Kuanoniamine A, Heterocycles, 2006, 68(5), 975-981.
  •    N. O. Townsend and Y. A. Jackson, Synthesis of a 9-Aza Analogue of Eleutherol, Heterocycles, 2007, 71(3), 669-675.
  •    N. K. Downer and Y. A. Jackson, Iodine-Mediated Cyclisation of Thiobenzamides to Produce Benzothiazoles and Benzoxazoles, Tetrahedron, 2007, 63(41), 10276-10281.
  •     N. K. Downer-Riley and Y. A. Jackson, Conversion of Thiobenzamides to Benzothiazoles via Intramolecular Cyclization of the Aryl Radical Cation, Tetrahedron, 2008, 64(33), 7741-7744.
  •   N. K. Downer-Riley and Y. A. Jackson, Highlight Syntheses, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2008, 104, 142-163.
  •    N. K. Downer-Riley and Y. A. Jackson, Highlight Syntheses, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2009, 105, 167-189.
  •    R. C. Higgins, N. O. Townsend and Y. A. Jackson, Benzylic Oxidation of N-Acyl-1,2,3,4-Tetrahydroquinolines, Heterocycles, 2009, 78(12), 3011-3021.
  •   J. A. Grant, T. Bonnick, M. Gossell-Williams, T. Clayton, J. M. Cook and Y. A. Jackson, Synthesis, Phamacological Studies and Molecular Modeling of some Tetracyclic 1,3-Diazepinium Chlorides, Bioorganic and Medicinal Chem., 2010, 18(2), 909-921.
  •   A. L. C. Morris and Y. A. Jackson, Synthesis of a 6H-Chromeno[3,4-b]quinoline and a 6a,12a-Dehydro-7-azarotenoid, Heterocycles, 2010, 81(2), 371 - 380.
  •    O. V. Barrett, N. K. Downer-Riley and Y. A. Jackson, Synthesis of Some Novel Benzobisthiazoles, Heterocycles, 2010, 81(7), 1641-1649.
  •    N. K. Downer-Riley and Y. A. Jackson, Highlight Syntheses, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2010, 106 (1), 174 – 196.
  •    A. L. C. Morris and Y. A. Jackson, Synthesis of Chromeno[3,4-b]quinolines: Electrophilic Aromatic Substitution under Heck Conditions, Synthesis, 2011, 2, 229-234.
  •    N. K. Downer-Riley and Y. A. Jackson, Highlight Syntheses, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2011, 107 (1), 157 – 181.
  •   N. K. Downer-Riley and Y. A. Jackson, “Selenium(IV) Oxide - tert-Butyl Hydroperoxide” in Update of the Encyclopaedia of Reagents for Organic Synthesis, John Wiley and Sons, Inc., New York, 2012.
  •    N. Downer-Riley and Y. A. Jackson, Highlight Syntheses, Annu. Rep. Prog. Chem., Sect. B: Org. Chem, 2012, 108, 147 – 170.
  •   O. V. Barrett, N. K. Downer-Riley and Y. A. Jackson, Thermally Induced Cyclization of Electron-Rich N-Arylthiobenzamides to Benzothiazoles, Synthesis, 2012, 44(16), 2579-2585.