Roy Porter

Senior Lecturer (Organic), Head of Department of Chemistry
B.Sc., Ph. D., U.W.I.,

 
Research Interests
Phytochemicals from Jamaican folklore medicinal plants and their biological activity.Identification of the constituents of Essential Oils from local aromatic folklore medicinal plants.Anti-oxidant activities of Jamaican plant extracts
 
Dr. Roy Porter's research group studies species of plant genera reputed to have folklore medicinal properties. These plants are examined for their essential oils and phytochemicals.
 
Of particular interest to the group are:

  1. The eight species of the Hyptis genus found locally; these species are verticillata, capitata, spicigera, suaveolens, atrorubens, brevipes, pectinata and mutabilis.
  2. The ten local species of the Cleome genus,  namely rutidosperma (consumption weed), viscosa, spinosa, serrata, aculeata, gynandra, hasslerana, houstonii, iberica and speciosa.
  3. The local species of the Bursera genus, simaruba (red birch), lunanii (black birch), aromatica and holickii.

 
The objective of the research is to find new compounds that have biological activity and to validate the folklore medicinal uses of the plants.
 
The group has thus far completed the investigation of the essential oils from the four species of the Bursera genus, four species from the Cleome genus and three species from the Hyptis genus. Phytochemical investigations are ongoing on various species from the three genera.
 
The group also has a minor research interest in endophytic fungi from mangrove plants, known to produce structurally diverse compounds with interesting  biological activity. The group has isolated endophytes from four different mangrove species, grown some of these endophytes in the lab and examined their extracts for anti-microbial, insecticidal and antioxidant activity. 
 
Selected Publications

  • M. Bakir, D. Biggs, A. Lough, W. Mulder, W. Reynolds and R.B.R. Porter, "7-Acetyl-12-methoxyhorminone from Jamaican Hyptis verticillata (Labiate)", Acta Cryst. 2006, E62, 306-308.
  • P.C. Facey, R.B.R. Porter, P.B. Reese and L.A.D. Williams, "Biological activity and Chemical composition of the Essential Oil from Jamaican Hyptis verticillata Jacq.", J. Agric. Food Chem. 2005, 53, 4774-4777.
  • M. Bakir, P. Facey, I. Hassan, W. Mulder and R.B.R. Porter, "Mikanolide from Jamaican Mikania micrantha", Acta Cryst. 2004, C60, 798-800.
  • M. Bakir, O. Green, C. Gyles, B. Mangaroo and R.B.R. Porter, "Nuclear Magnetic Resonance and optosensing properties of di-2-thienylketone p-nitrophenylhydrazone (DSKNPK) in non-aqueous media", Talanta, 2004, 62, 781-789.
  • L.A.D. Williams, E. Vasques, W. Reid, R.B.R. Porter and W. Kraus, "Biological activity of a leaf surface extrudes extract of Cleome viscosa (Capparaceae)", Naturwissenshaften, 2003, 90 (10) , 468-472.
  • R.B.R. Porter, W.A. Gallimore and P.B. Reese, "Steroid transformation with Exophiala jeanselmei var. lecaniicorni and Ceratocystis paradoxa", Steroids, 1999, 64, 770-779.
  • R.B.R. Porter, P.C. Facey, K.O. Pascoe and A.D. Jones, "Investigation of Jamaican folk-medicine for anti-bacterial activity", Pharmacy and Pharmacology, 1999, 51, 1455-1460.
  • R.B. Porter, P. B. Reese, "Characterization of a Flavonol and Several Lignans from Hyptis verticillata", Jamaican Journal of Science and Technology, 1998, 9, 17-27.
  • R.B. Porter, P. B. Reese, L.A. D. Williams and D. J. Williams, "Acaricidal and Insecticidal Activities of Cadina-4, 10(15)-dien-3-one", Phytochemistry, 1995, 40, 735. Read More