K Hoe

Gentamicin Therapeutic Drug Monitoring: Importance in the Hospital Setting

Issue:

Vol 66, Issue 2: 2017

DOI:

10.7727/wimj.2015.603

Pages:

324–8

Synopsis:

Gentamicin has a propensity to induce nephrotoxicity. This study showed that most of the patients treated with gentamicin experienced some levels of nephrotoxicity and suggests the need for the vigilant monitoring of serum creatinine in such patients in a hospital setting without therapeutic drug monitoring facilities.

ABSTRACT

Background: Use of gentamicin places patients at risk of developing drug-induced nephrotoxicity, requiring special consideration to be given to serum creatinine monitoring and therapeutic drug monitoring (TDM).

Objectives: To evaluate the prevalence of nephrotoxicity without the availability of TDM.

Received:

10 Dec, 2015

Accepted:

02 Feb, 2016

Published:

22 Sep, 2017

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