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CTLA-4

Investigation of CTLA-4 and CD28 Gene Polymorphisms in Patients with Diabetes Mellitus Type 2 Using PCR-RFLP in a Turkish Population

Issue: 
Pages: 
235–40
Synopsis: 
The CTLA-4 gene c.49A >G and c.-319C >T, and CD28 gene c.534+17T >C polymorphisms did not represent an important risk factor for this disease in a Turkish population.

ABSTRACT

Objective: The aim of this study is to investigate whether specific polymorphisms in the CTLA-4 and CD28 gene are associated with Type 2 diabetes mellitus (T2DM).

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e-Published: 07 Oct, 2013
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