Comprehensive treatments for visceral metastatic carcinoma of unknown primary site (VMCUP) including surgery and chemotherapy significantly improved patients’ overall survival time. Patients treated mainly by surgery lived longer than those treated by chemotherapy alone. More chemotherapy cycles resulted in longer survival time for patients only receiving chemotherapy. For the first time, this study identified paclitaxel plus fluorouracil as more effective first-line chemotherapy drugs than 5-fluorouracil in treating VMCUP.

Morphine at concentrations of 2 μmol/L and 4 μmol/L after coronary perfusion on cardiac valve replacement with cardiopulmonary bypass has myocardial protection.

GRP78 protein is widely present in human testis, epididymis and spermatozoa. Capacitation and acrosome reaction didn’t affect the location of GRP78. Positioning percentage and signal intensity of GRP78 on sperm were significant positive correlation with sperm progressive motility and vitality.