rat

Effect of Hydro-alcoholic Extract from Prosopis Farcta Leaves on Liver Injury Caused by High-fat Diet in Rats

Issue:

Vol 68, Issue 1: 2019

DOI:

10.7727/wimj.2016.507

Pages:

13-9

Synopsis:

The hydro-alcoholic extract of the leaves of Prosopis farcta was evaluated for hepatoprotective and antioxidant activities in rats submitted to a high-fat diet. Oral administration of extract of Prosopis farcta leaves resulted in significant amelioration of the altered indices.

ABSTRACT

Objective: To determine the hepatoprotective and antioxidant effects of hydro-alcoholic extract of Prosopis farcta (P farcta) leaves on high fat diet-fed (HFDF) rats.

Received:

07 Oct, 2016

Revised:

13 Jun, 2017

Accepted:

13 Nov, 2017

Published:

07 Oct, 2019

PDF Attachment:

wimj-iss1-2019_13_19.pdf

Journal Sections:

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e-Published: 15 Nov, 2017

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The Effect of Borax on Hematological Parameters and Immunoglobulin Values in Rats

DOI:

10.7727/wimj.2016.359

Synopsis:

Boron supplementation in animal and human nutrition may have important effects on various metabolic, physiological systems of the organism. The aim of this study was to evaluate the effect of borax on hematological parameters and immunoglobulin values in the rats.

ABSTRACT

Objective: Boron is an essential metalloid which plays a key role in plants and animals metabolisms. In the last few years boron compounds became increasingly more frequent in some hematological diseases. The aim of this study was to evaluate the effect of borax as a boron source on hematological parameters and immunoglobulin (Ig) values in the rats.

Received:

07 Jul, 2016

Accepted:

12 Aug, 2016

PDF Attachment:

keklik_et_al-boron_supplementation_in_animal_and_human_nutrition.pdf

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e-Published: 12 Aug, 2016

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Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Immunohistopathological and Biochemical Study of the Effects of Dead Nettle (Urtica Dioica) Extract on Preventing Liver Lesions Induced by Experimental Aflatoxicosis in Rats

Issue:

Vol 67, Issue 3: 2018

DOI:

10.7727/wimj.2016.126

Pages:

254-61

Synopsis:

This paper studied the preventive effects of dead nettle extract on liver lesions that were induced by experimental aflatoxicosis in rats. According to the biochemical and histopathological findings of the study, antioxidant system activity increased and lipid peroxidation and liver enzyme levels decreased in the group that received dead nettle leaf extract. As a result, it could be concluded that dead nettle leaf extract had hepatoprotective effects against aflatoxicosis.

ABSTRACT

Objective: Aflatoxicosis is a mycotoxicosis infection with an acute or chronic course that forms due to aflatoxins (AFs) in humans and animals. Aflatoxins primarily affect the liver and can lead to histopathological necrosis, fibrosis and hepatocarcinogenesis of the organ. This paper studied the preventive effects of dead nettle leaf (Urtica dioica leaf; UDL) extract on liver lesions that were induced by experimental aflatoxicosis in rats.

Received:

22 Mar, 2016

Accepted:

25 May, 2016

Published:

14 Nov, 2018

PDF Attachment:

wimj-iss3-2018_254_261.pdf

Journal Sections:

Original Articles

Keywords:

Aflatoxicosis

extract of dead nettle leaf

Journal Authors:

e-Published: 13 Jul, 2016

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Short-term Administration of Gonadotropin-releasing Hormone Agonist (Buserelin) Induces Apoptosis in Rat Ovarian Developmental Follicles

Issue:

Vol 69, Issue 5: 2021

DOI:

10.7727/wimj.2016.170

Pages:

319-25

Synopsis:

The short-term administration of high dose buserelin decreases the number of follicles in mature rat ovaries and has an inhibitory effect on follicular development. Also, the buserelin increases apoptosis in the granulosa cells and serum estradiol (E2) level, but the serum progesterone levels decrease.

ABSTRACT

Objective: To investigate the effects of buserelin on the development of follicles, apoptosis index and steroid hormones level.

Received:

19 Apr, 2016

Accepted:

15 Jun, 2016

Published:

12 Nov, 2021

PDF Attachment:

wimj-iss5-2021_319_325.pdf

Journal Sections:

Original Articles

Keywords:

Gonadotropin-releasing hormone agonist

enzyme-linked immunosorbent assay

Journal Authors:

e-Published: 30 Jun, 2016

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The Effects on Offspring of Diabetes Mellitus Induced by Chemical Agents in Rats with Advanced Pregnancy

Issue:

Vol 69, Issue 1: 2021

DOI:

10.7727/wimj.2015.587

Pages:

56-9

Synopsis:

Diabetes is the most important cause of perinatal mortality, and a four- to eight-fold greater malformation rate is observed among babies of diabetic mothers than among the general population. Cardiac anomalies and central nervous system anomalies are the most common anomalies observed in babies of diabetic mothers.

ABSTRACT

Background: Gestational diabetes mellitus is an increasingly frequent metabolic disorder that is important for both baby and mother. New studies on the development and treatment of the disease are required.

Objective: To investigate the effects on offspring’s survival and the biochemical values of diabetes mellitus, induced by different doses of two chemical agents among 35 rats with advanced pregnancy.

Received:

03 Dec, 2015

Accepted:

07 Dec, 2015

Published:

30 Apr, 2021

PDF Attachment:

wimj-iss1-2021_56_59.pdf

Journal Sections:

Keywords:

Journal Authors:

e-Published: 30 Mar, 2016

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Histopathological Changes that Occur on the Testicular and Penile Tissues Depending on the Treatment of Human Chorionic Gonadotropin: Rat Model

Issue:

Vol 69, Issue 5: 2021

DOI:

10.7727/wimj.2015.282

Pages:

315-8

Synopsis:

Human chorionic gonadotropin (hCG) treatment may lead to deterioration in testicular histology and histological changes in the penile tissue. The degradation in the testicular tissue and the changes formed in the penile tissue may affect the erectile tissue function.

ABSTRACT

Objective: To examine the histopathological effects of human chorionic gonadotropin (hCG) treatment on the penile and the testicular tissue in rat model.

Received:

29 May, 2015

Accepted:

11 Sep, 2015

Published:

12 Nov, 2021

PDF Attachment:

wimj-iss5-2021_315_318.pdf

Journal Sections:

Original Articles

Keywords:

histopathology

human chorionic gonadotropin

Journal Authors:

e-Published: 22 Mar, 2016

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Effect of Yi Fu Kang Oral Liquid on Gastrointestinal Side Effects Caused by Chemotherapy

DOI:

10.7727/wimj.2015.076

Synopsis:

Yi Fu Kang oral liquid can enhance the function of the gastrointestinal tract of animals by reducing the number of emetic responses, protecting the gastric mucosa and propelling movement of small intestine contents.

ABSTRACT

Objective: We aimed to investigate whether Yi Fu Kang oral liquid (YFK) could reduce the gastrointestinal side effects caused by chemotherapy.

Received:

03 Feb, 2015

Accepted:

26 Mar, 2015

PDF Attachment:

hao_et_al-herb_effect_on_side_effects_by_chemotherapy.pdf

Journal Sections:

Original Articles

Keywords:

rat

Gastrointestinal reaction

pharmacodynamics

pigeon

Yi Fu Kang oral liquid

Journal Authors:

e-Published: 23 Oct, 2015

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Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Different Doses and Routes of Administration of Methimazole Affect Thyroid Status in Methimazole-induced Hypothyroidism in Rats

Issue:

Vol 65, Issue 1: 2016

DOI:

10.7727/wimj.2014.241

Pages:

93–7

Synopsis:

In the present study, we established and compared differences of the rat’s hypothyroid model induced by MMI added to drinking water or given through an intragastric tube.

ABSTRACT

Objective: It is agreed that methimazole (MMI) can be administered to induce hypothyroidism. However, there are conflicting data about its effect on thyroid function and development in rats through different administrations. In the present study, we established and compared differences of the rat hypothyroid model induced by MMI added to drinking water or given through an intragastric tube.

Received:

06 Oct, 2014

Accepted:

31 Oct, 2014

PDF Attachment:

wimj_iss1_2016_93_97.pdf

Journal Sections:

Keywords: