This paper presents an overview of the model of quality assurance at The University of the West Indies (UWI) as developed by the Office of the Board for Undergraduate Studies (OBUS). “Fitness for purpose” is the definition of quality that informs the articulation and operationalization of the UWI model, and the authors engage in a critical examination of the processes involved. These processes include self-assessment, peer review, and site visits, and the follow-up of the recommendations of review reports. The authors discuss the intended and actual outcomes of the UWI model of quality assurance, with a focus on the impact of programme review on the quality of teaching and learning, and identify wise practices across the three residential campuses. They reflect on the successes, constraints, and challenges of quality assurance at the UWI.