Introduction
Kidney stones have become increasingly prevalent over the past two decades with the prevalence rate worldwide being approximately 1.7% to 8.8%(1). Fifty percent (50%) of individuals that have had renal calculi will have a recurrence(2). Stones such as Calcium Oxalate are idiopathic(3). This study aims to identify the composition and concentration of elements present in calcium oxalate stones.
Method
In this study 28 kidney stones were collected from 14 participants. The stones were rinsed in deionized water for 2 minutes and then left to air dry for 10 minutes. They were afterward rinsed in 75% Isopropyl alcohol for 5 minutes and then left to air dry for 10 minutes. Quality control was carried out on the XRF unit to assess its accuracy and repeatability. A non-destructive approach was taken to analyse the kidney stones. The stone samples were placed on a 12μm thick Mylar sheet and positioned over the x-ray window of the XRF unit. Each kidney stone sample was measured four times, twice on each surface. The results were averaged and recorded.
Results & Discussion
Calcium was the most abundant element detected followed by phosphorous. Other elements detected in the kidney stone samples included Potassium, Scandium, Silicon, Zinc, Chlorine, Tungsten and Sulphur.
Conclusion
The data indicated the ability of XRF technology to determine the elemental composition of kidney stones forelements with atomic number greater than 14 and at concentration as low as 0.01%.
Relevance of Study
By understanding the elemental compositionand concentrationof Calcium Oxalate stones, potential statistical relationship between the elements could be used to create mathematical and statistical models which would help to better understand their formation.
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