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Application of Two-Stage Hybrid Coronary Revascularization in Multivessel Coronary Artery Disease



Objective: The aim of this study was to explore the efficacy of percutaneous coronary intervention (PCI) with minimally invasive direct coronary artery bypass grafting (MIDCABG) in the treatment for multivessel coronary artery disease (CAD).

Methods: Clinical data was collected from 208 patients with multivessel CAD involving left anterior descending coronary artery (LAD) who underwent PCI between January 2012 and January 2014. There were 16 patients undergoing two-stage hybrid coronary revascularization (HCR) and another 16 paired patients undergoing PCI alone as control. All the patients in HCR group underwent MIDCABG and 3-7 days antiplatelet therapy followed by PCI.

Results: No death and severe complications were observed in 16 patients undergoing HCR, who had longer hospital stay (11.88 ± 1.15 vs 7.19 ± 1.11 days) and higher medical expense (103186.16 ± 8743.86 vs 64645.66 ± 4929.50 yuan) compared with PCI group. During 3–24 months follow-up, there were no death and myocardial infarction in both groups, but an attack of angina occurred in one patient in PCI group who afterwards underwent coronary angiography and second PCI with implantation of drug-eluting stents due to in-stent restenosis.

Conclusions: Two-stage HCR is a safe, effective and minimally invasive method to treat multivessel CAD.

11 Sep, 2015
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e-Published: 18 Sep, 2015


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