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Effect of Antioxidant on Coronal Seal of Dentin Following Sodium Hypochlorite and Hydrogen-Peroxide Irrigation



Aim: Comparative analysis of the coronal microleakage of a self-etching priming dentin adhesive with the use of antioxidant (Sodium Ascorbate (SA) and herbal quercetin) after Sodium hypochloride (NaOCl) and hydrogen-peroxide (H2 O2) irrigation.   

Materials and Methods: Seventy single root canals were enlarged and seven different treatment protocols were applied throughout the root canal treatment. The groups 1, 2 and 3 were irrigated with NaOCl. Group 1 was used as the negative control with only NaOCl irrigation whereas in group 2, Sodium Ascorbate was applied as an additional irrigation agent following NaOCl. In group 3, herbal antioxidant Quercetin (Q) was applied as an additional irrigation agent following NaOCl. Hydrogen-peroxide irrigation was used in groups 4, 5 and 6, the procedural steps were similar to those of groups 1, 2 and 3: H2 O2 in group 4, Sodium Ascorbate application in group 5 and herbal antioxidant Quercetin group 6. Group 7 was positive control with saline irrigation alone. All root were obturated with A-H Plus root canal sealer and protaper F4 gutta-percha cones immediately after irrigation. A self-etching priming adhesive plus ceram-x mono composite resin was applied after the endodontic treatment. The microleakage of dentin margins was determined using dye-penetration test under microscope.

Statistical Analysis: In this study, Kruskal-Wallis test, Mann-Whitney U and Wilcoxon W tests were used.

Results:  Kruskal-Wallis test with p = 0.000 indicated that a significant difference exists between all the seven groups. NaOCl, H2 O2 groups demonstrated higher leakage scores than the controls (p < 0.005). Leakage pattern of groups 2, 3, 5 and 6 did not differ significantly from the control (p > 0.05).

Conclusion: After control group 7, group 2 showed significantly less amount of dye penetration as compared with the other groups.

29 Jul, 2015
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e-Published: 15 Oct, 2015


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