Close Menu

Books in a Library

Ovarıan Granulosa Cell Tumors: Evaluatıon of Clınıcal, Outcome and Reccurence Factors



Objective: We aimed to determine the predictors for poor prognosis and to find out the effect of treatment strategies on survival functions

Methods: Thirty seven women with granulosa cell tumor were enrolled for the study between 2000 and 2013. All data was obtained from hospital prospectively collected databese.

Results: The mean age was 50.1±13.3 and the most common symptom was abdominal distansion ( 21.6%) . Mean follow up period was 67.9±33.6 months.  During follow up period

Disease specific mortality was observed in only 1 (2.7%) patient and recurrence was observed in 7 patients (18.9 %).  Comparison of the groups with and without recurrence revealed significant differences in terms of stage, capsule involvement, mitotic index between groups (p<0.05). In multivariate regression analyses tumor differentiation was found to be significantly associated with the disease recurrence (OR:8.2,CI 95%: 0,019-0,771).

Conclusion: Tumor differentiation is found to be a significant confounder for the disease recurrence after adjustment for the   stage.

07 Sep, 2015
PDF Attachment: 
e-Published: 28 Jan, 2016


Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Top of Page