Close Menu

The Effect of Continuous Positive Airway Pressure on Basal Metabolism Rate in Patients with Severe Obstructive Sleep Apnea Syndrome

DOI: 
10:7727/wimj.2015.489

ABSTRACT

Objectives: The aim of this study was to assess the effect of the continuous positive airway pressure (CPAP) treatment on basal metabolism rate in patients with severe obstructive sleep apnea syndrome (OSAS).

Methods: Demographic characteristics, body-mass index (BMI), apnea-hypopnea index (AHI) and smoking history of the patients were recorded.  Basal metabolism rate was measured via indirect calorimetry in the morning following the nights of polysomnography and CPAP titration. Basal metabolism rate, VO2 and VCO2 levels were compared before and after CPAP administration.

Results: Six (24%) female and 19 (76%) male, totally 25 patients with mean age of 51.4 ± 13.7 years were included into the study. A significant reduction in the basal metabolism rate (p=0.049), VO2 (p=0.042) and VCO2 (p=0.008) values were observed after single night administration of CPAP compared to before treatment. Furthermore, it was detected that this reduction provided by CPAP treatment was more significant in current smokers, patients with AHI>60 and BMI ≥ 30.

Conclusion: It is suggested that there is a correlation between basal metabolism rate and the severity of OSAS and it is possible to provide significant reduction in basal metabolism rate with single night administration of CPAP depending on the patient’s smoking history, degree of obesity and disease severity.

 

Accepted: 
02 Nov, 2016
PDF Attachment: 
e-Published: 08 Feb, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Top of Page