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Uncontrolled Systemic Inflammatory Response Syndrome by Cardiopulmonary Bypass

Journal Authors: 


It is known that the use of a cardiopulmonary bypass (CPB) during cardiac surgery leads to leukocyte activation and may, among other causes, induce organ dysfunction due to increased leukocyte recruitment into different organs. In our patients pathophysiologically severs SIRS, uncontrolled CPB induced inflammation, chylomicrons and very low density lipoproteins (VLDL) or immune complex have been shown to develop immune dependent agglutination by C-reactive proteins in cardiopulmonary bypass, which could result in vascular occlusion and resultant infarction.



10 Sep, 2015
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e-Published: 15 Feb, 2016


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