ABSTRACT
Objective: The pressure requirements for patients with obstructive sleep apnea syndrome (OSAS) who use a positive airway pressure (PAP) device may change over time for various reasons. We determined the optimal time for a controlled titration study and its associated factors in patients with OSAS using a PAP device.
Methods: We retrospectively identified 82 patients diagnosed with OSAS who used a PAP device and underwent a second PAP titration study for control purposes at our sleep center. The demographic characteristics and anthropometric measurements of the patients during first and second PAP titration studies were recorded. We compared pressures and BMI values after both titration tests.
Results: The patients were divided into three groups according to the pressure changes following the second titration study: those with elevated, unchanged, and decreased PAP pressure. The BMI calculated following both studies increased significantly in the group with elevated pressure (p < 0.001), decreased significantly in the group with decreased pressure (p < 0.001), and no significant difference was observed in the group with unchanged pressure (p = 0.235). A positive correlation was found between the change in BMI and the change in Cpap, Ipap, and Epap values following both titration tests (p < 0.001, r = 0.898; p < 0.001, r = 0.884; p < 0.001, r = 0.896, respectively).
Conclusion: The results show that weight changes in patients with OSAS receiving PAP therapy during follow-up can be accompanied by pressure changes in the device, suggesting the need for a second controlled titration test.
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.
Our 7 faculties and 12 professional schools offer more than 200 programmes to some 18,000 graduate, undergraduate and continuing studies students.
The UWI, Mona ranks first in Jamaica among accredited tertiary-level programmes. In 2012, the University was again one of Jamaica’s Top 100 Employers.
