Close Menu

A “Full House” Glomerulopathy in a Patient with Multiple Lentigenes Syndrome: A Case Report

Issue: 
DOI: 
10.7727/wimj.2016.001

ABSTRACT

Multiple Lentigines syndrome (MLS) is an autosomal dominant disease which is usually diagnosed clinically by the presence of characteristic features. The molecular genetic testing is an adjuvant diagnostic tool to identify the mutation of particular genes such as PTPN11 genes, RAF1, BRAF or MAP2K1 genes (1-4). This syndrome is formerly known as LEOPARD syndrome or Noonan syndrome with multiple Lentigines (NSML). Leopard Syndrome is an acronym of characteristic features (Lentigines, Electrocardiographic conduction abnormalities, Ocular hypertelorism, Pulmonary stenosis, Abnormalities of the genitalia, Retardation of growth and Deafness) which was introduced by Grolin and colleagues in 1969 (5). There was no previous case report about any glomerulonephropathy in association with Multiple Lentigines Syndrome. Herein, we present a case of multiple lentigenes syndrome with recurrent nephrotic syndrome who is found to have histologic evidence of full house glomerulopathy. 

Accepted: 
11 Jan, 2016
e-Published: 23 Feb, 2016

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Become a subscriber to access the full article.

Top of Page