ABSTRACT
One of the perforating dermatoses (PD) is acquired reactive perforating collagenosis (ARPC). Clinical presentations of ARCP are umbilicated papules or nodules with a central adherent keratotic plug containing cellular debris and collagen. The disease group is histopathologically characterized by transepidermal elimination of various dermal substances into cup-shaped epidermal invagination. PD is usually associated with diabetes mellitus (DM) or chronic renal failure (CRF). In recent years, it has also been reported to be associated with some other metabolic, endocrinological and infectious diseases and malignancies. Herein, we report a 62-year- old woman with ARPC whose lesions were associated with longlasting chronic hepatitis B virus (HBV) infection, cirrhosis, and sigmoid colon displastic adenoma. To the best of our knowledge these associations have not been reported previously.
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