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Gorlın’s Syndrome wıth Aggressıve Basal Cell Carcınoma: A Case Report



Gorlin’s Syndrome (basal cell nevus syndrome) is a rare autosomal dominant disease which characterized with multiple basal cell carcinomas (BCC), maxillamandibular odontogenic keratocysts, palmoplantar pits and various skeletal anomalies. Despite its frequency, BCC has a low mortality rate because of its slow progression and minimal soft tissue invasion,  however, it can occasionally show aggressive course with deep invasions, metastasis and recurrences. In this article we reported a Gorlin’s syndrome case which presents with BCC , showing  perineural invasion and relapsing consistently after surgical treatments. Our aim is to remind the hereditary diseases in the early onset cases with multiple BCC and to draw attention to aggressive course of BCC which located especially in periorbital and perinasal areas.


15 Jun, 2016
e-Published: 28 Jun, 2016


Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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