ABSTRACT
Objective: To evaluate the clinical effects of radiofrequency ablation (RFA) for transarterial chemoembolization (TACE) postoperative residual tumor in liver cancer.
Methods: A retrospective analysis was performed involving patients with a diagnosis of primary liver cancer who received interventional therapy in the Invasive Technology Department of the Third Affiliated Hospital of Wenzhou Medical University from January 1, 2010 to January 1, 2013. The patients receiving only TACE treatment (43 cases) comprised the TACE group, and patients who received TACE and RFA combined treatment (31 cases) made up the combined treatment group. A comparative analysis assessing therapeutic effect, progression-free survival (PFS), overall survival (OS) and adverse reactions was conducted between the two groups.
Results: The objective remission rate of the combined treatment group (87.1%) was higher than that of the TACE group (65.1%; P < 0.05). The median PFS (19 months) and median OS (33 months) of the combined treatment group were higher than those of the TACE group (median PFS 14.5 months and median OS 29 months; both P<0.05). The incidence rate of adverse reactions, such as albumin decline and total bilirubin increase, was lower in the combined treatment group than that in the TACE group (P<0.05).
Conclusion: RFA can efficiently clear the TACE postoperative residual tumor and prolong both PFS and OS.
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