Close Menu

Salivary IgA and Total Protein in Human Subjects with Oral Lichen Planus and Squamous Cell Carcinoma

DOI: 
10.7727/wimj.2016.230

ABSTRACT

Purpose: The purpose of this study was to compare salivary immunoglobulin A (IgA) and total protein (TP) in patients suffering from oral lichen planus (OLP) and oral squamous cell carcinoma (OSCC), against healthy control.

Methods: In a case-control study, 20 patients with OSCC, 30 patients suffering from OLP and 50 non-involved subjects were enrolled. The mean stimulated and unstimulated saliva IgA and TP levels were assayed by the Biuret method and immunoturbidometry respectively. Statistical analysis of the ANOVA was performed.

Results: The mean concentration of stimulated and unstimulated saliva IgA and TP were significantly higher in both OLP and OSCC patients compared to control. Additionally TP, but not IgA, was higher in patients with OSCC compared with OLP patients d more salivary TP than OLP patients.

Conclusion: Results suggest that salivary TP but not IgA is higher in OSCC patients than OLP patients.

Accepted: 
30 Jun, 2016
PDF Attachment: 
e-Published: 19 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Top of Page