Close Menu

The Role of Cardioselective Beta Blockers in Cardiopulmonary Exercise Test and Echocardiography in COPD Patients

DOI: 
10.7727/wimj.2016.348

ABSTRACT

Objective: The aim of this study was to evaluate the effects of cardioselective β-blockers in echocardiography and cardiopulmonary exercise tests (CPET) in COPD patients.

Methods: Patients with COPD admitted to Pulmonary Diseases and Cardiology department between January 2011 and January 2013 were enrolled in this study. Group I included the patients with COPD (n: 26); group II included COPD patients with accompanying heart disease with no use of β-blockers (n: 25); group III included COPD patients with accompanying heart disease treated with cardioselective β-blocker (metoprolol) (n: 22). Age, height, weight and medical history of all patients were recorded; and routine laboratory tests, CPET, and echocardiography were performed. In the first year, the tests were repeated using the same devices and protocols.

Results: There were 73 patients in study, 4 (5.5%) female and 69 (94.5%) male. The average age of the patients was 63±8 years. According to GOLD criteria, 4 (5.5%) patients were in stage 1 COPD, 30 (41.1%) patients in stage 2, 23 (31.5%) patients in stage 3, and 16 (21.9%) patients were in stage 4. The COPD patients with accompanying heart disease (Group II and III) had significantly higher pro-BNP values than group I patients. The basal and final values of echocardiography and CPET after one year did not differ significantly in all study groups (p>0.05).

Conclusions: This study suggests that the cardio-selective β-blockers, which are contraindicated in COPD patients, are safe and do not affect CPET and echocardiography measurements. 

Accepted: 
12 Aug, 2016
PDF Attachment: 
e-Published: 12 Aug, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Top of Page