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Pseudomonas aeruginosa Resistance to Various Commonly used Antibiotics in 27 Hospital Patients

DOI: 
10.7727/wimj.2016.450

ABSTRACT

Objective: The aim of this study was to use wound swabs to determine antibiotic resistance patterns in Pseudomonas aeruginosa, which has been shown to be highly resistant to many commonly used antibiotics.

Methods: This study observed 27 isolates of the gram-negative bacteria Pseudomonas aeruginosa and tested their resistance to various commonly used antibiotics. The strains were isolated from surgical patients of both sexes and different age groups. Patients were hospitalized in various departments (Department of Internal Medicine, Pediatrics, Dermatology, Ear, Nose and Throat, Neurology, Orthopedics, Oncology, and Physical and Rehabilitation medicine) at our hospital.

Results: According to the resistance patterns found, the most effective antibiotic in our sample population was colistin (100% sensitivity), followed by amikacin (88% sensitivity), tobramicin (81% sensitivity). The least effective antibiotics were found to be carbapenems (8% sensitivity) and ciprofloxacin (12% sensitivity).

Conclusion: The isolates of Pseudomonas aeurginosa show a high degree of resistance (>50% resistance) to commonly used antibiotics such as imipenem and meropenem, ciprofloxacin, gentamicin, netilmicin and piperacillin.

Accepted: 
05 Oct, 2016
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e-Published: 02 Nov, 2016

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