ABSTRACT
Non-compaction of the left ventricle is a rare newly diagnosed cardiomyopathy (Grant 1926), and a significant cause of end stage triad of arrhythmias, heart failure, and systemic emboli. Twenty percent (20%) having ventricular tachycardia leading to sudden death being one of the presenting signs and two-thirds having supraventricular arrhythmias. The familial forms can be X-linked, Autosomal Dominant or Autosomal recessive, with a variable genotype-phenotypic expression and sporadic mutations in sarcomere protein genes which are similar to hypertrophic, dilated and restrictive cardiomyopathy. The index case presented with increasing palpitations, heart failure at 21 years of age. This is the 1st Case of isolated non-compaction of the left ventricle documented in an Afro-Caribbean.
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