Non-compaction of the left ventricle is a rare newly diagnosed cardiomyopathy (Grant 1926), and a significant cause of end stage triad of arrhythmias, heart failure, and systemic emboli. Twenty percent (20%) having ventricular tachycardia leading to sudden death being one of the presenting signs and two-thirds having supraventricular arrhythmias. The familial forms can be X-linked, Autosomal Dominant or Autosomal recessive, with a variable genotype-phenotypic expression and sporadic mutations in sarcomere protein genes which are similar to hypertrophic, dilated and restrictive cardiomyopathy. The index case presented with increasing palpitations, heart failure at 21 years of age. This is the 1st Case of isolated non-compaction of the left ventricle documented in an Afro-Caribbean.
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.