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Initial Experience and Outcomes with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for the Management of Peritoneal Carcinomatosis in the Bahamas

DOI: 
10.7727/wimj.2015.522

ABSTRACT

Background: Cytoreductive Surgery (CRS) with heated intraperitoneal chemotherapy (HIPEC) is a treatment option with curative intent for selected patients with peritoneal carcinomatosis (PC). The aim of our study was to report our initial experience with CRS and HIPEC performed by a specialized team in a low volume setting. We set out to determine the safety and efficacy of this treatment and also look at our outcomes with respect to perioperative complications and survival.

Methods: A prospective database of patients treated with CRS and HIPEC was maintained since 2010. Demographic, tumor and treatment factors as well as postoperative outcomes were prospectively recorded.

Results: Between 2010 and 2015 a total of seven patients underwent CRS and HIPEC. PC originated from colorectal carcinoma in five patients and appendix cancer in two patients. Mean age was 52 years, median peritoneal carcinoma index (PCI) was 13, mean operative time was 662 minutes and median blood loss was 1300 cc. Fourteen percent of patients developed a complication, there were no 30 day mortality.  The median length of stay was 14 days. After an overall 19 month follow-up the overall mean survival was 48.83 months.

Conclusion: CRS and HIPEC seems a safe procedure for PC in the Bahamas. Favorable long-term survival was achieved in this population of highly selected patients with PC. 

Accepted: 
26 Oct, 2015
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e-Published: 18 May, 2017

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