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The Reduction of the Demand of Nicotine Due to Pregabalin and Gabapentin: Two Cases



Pregabalin and gabapentin, it’s pharmacological like drug are new generation antiepileptic drugs. They show their effects through voltage-gated calcium channels. Sedation and cognitive dysfunction are among their side effects. There are some investigations shows that pregabalin and gabapentin may help to quit smoking. In this article two patients are presented. One of them smoked 60 cigarettes per a day for ten years and her urge to smoke decreased after pregabalin treatment and she quitted smoking.  The other one smoked 40 cigarettes per a day for 20 years and his urge to smoke decreased after gabapentin treatment and he quitted smoking. Moreover, the use of pregabalin and gabapentin in the treatment of smoking cessation is discussed through their side effects. 

09 Mar, 2015
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e-Published: 18 May, 2017


Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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