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The Effect of Obesity and Body Mass Index on Post-transplant Renal Graft Function

DOI: 
10.7727/wimj.2017.196
Pages: 

ABSTRACT

Objective: The aim of this five-year study was to investigate the influence of BMI and obesity on post-transplant renal graft function.

Methods: This research monitored 500 patients of both sexes who had received kidney transplants. Post-transplant measurements of the recipients’ biochemical parameters, anthropometric parameters, and renal function were performed. Also applied were two methods for assessing renal function: (i) the Cockcroft-Gault formula; (ii) serum creatinine clearance.

Results: Five years after transplantation, the patients showed an increase in obesity, accompanied by a lower glomerular filtration rate. Although the Cockcroft-Gault values were mild, the GFR percentage tended to decrease from the first to the fifth year, with higher serum creatinine levels.

Conclusions: The results reflected an increase in body weight and BMI in the five years after transplantation. This led to a lower glomerular filtration rate and subsequent graft damage during this time period.

Accepted: 
18 Dec, 2017
e-Published: 20 Dec, 2017

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Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

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