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The Effect of Obesity and Body Mass Index on Post-transplant Renal Graft Function

DOI: 
10.7727/wimj.2017.196
Pages: 

ABSTRACT

Objective: The aim of this five-year study was to investigate the influence of BMI and obesity on post-transplant renal graft function.

Methods: This research monitored 500 patients of both sexes who had received kidney transplants. Post-transplant measurements of the recipients’ biochemical parameters, anthropometric parameters, and renal function were performed. Also applied were two methods for assessing renal function: (i) the Cockcroft-Gault formula; (ii) serum creatinine clearance.

Results: Five years after transplantation, the patients showed an increase in obesity, accompanied by a lower glomerular filtration rate. Although the Cockcroft-Gault values were mild, the GFR percentage tended to decrease from the first to the fifth year, with higher serum creatinine levels.

Conclusions: The results reflected an increase in body weight and BMI in the five years after transplantation. This led to a lower glomerular filtration rate and subsequent graft damage during this time period.

Accepted: 
18 Dec, 2017
e-Published: 20 Dec, 2017

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