ABSTRACT

Objective: The aim of this five-year study was to investigate the influence of body mass index (BMI) and obesity on post-transplant renal graft function.

Methods: This research monitored 500 patients of both genders who had received kidney transplants. Post-transplant measurements of the recipients’ biochemical parameters, anthropometric parameters and renal function were performed. Two methods were also applied for assessing renal function: (a) the Cockcroft–Gault formula and (b) the serum creatinine clearance.

Results: Five years after transplantation, the patients showed an increase in obesity, accom panied by a lower glomerular filtration rate (GFR). Although the Cockcroft–Gault values were mild, the GFR percentage tended to decrease from the first to the fifth year, with higher serum creatinine levels.

Conclusions: The results reflected an increase in body weight and BMI in the five years after transplantation. This led to a lower GFR and subsequent graft damage during this time period.