ABSTRACT
Diffuse Pigmented Villo-Nodular Synovitis (PVNS) is a pan-articular disease with a natural history of degenerative changes in the long-term, that is, secondary osteoarthritis. Its peak incidence occurs in the fourth and fifth decade preceding that of primary osteoarthritis by 10-20 years. It tends to be mono-articular in presentation and has a high risk of recurrence. Identifying patients with secondary osteoarthritis and investigating for an underlying cause is the first step in avoiding undue morbidity in this patient population. The presentation of PVNS does not differ much from other causes of secondary osteoarthritis often resulting in a delay in diagnosis. It is therefore of great importance that a high index of suspicion be maintained as early detection of the disease process may allow joint conservative management options.
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.
Our 7 faculties and 12 professional schools offer more than 200 programmes to some 18,000 graduate, undergraduate and continuing studies students.
The UWI, Mona ranks first in Jamaica among accredited tertiary-level programmes. In 2012, the University was again one of Jamaica’s Top 100 Employers.
