Metastatic tumours of the parotid gland represent an extremely rare pathological entity. The majority of metastatic tumours of the region in question includes metastases of squamous cellular carcinoma and skin melanoma of the temporal region and the scalp, the described metastasis of liposarcoma represents a quite rare pathological entity. A 58-year-old female patient with a tumefaction in the parotid region was sent to the Clinic of Maxillofacial Surgery. Having examined the available medical records, it was found that the patient had been operated on three times. All surgeries were on the soft tissue of the right lower leg, with the last one being the amputation with a histopatohologically confirmed myxoid liposarcoma. The clinical case conference decided to conduct postoperative chemoradiation therapy due to the extensiveness of the tumour and endangered vital structures. Despite the conduction of appropriate postoperative procedures, radical surgical procedure, and postoperative oncological therapy, metastatic tumours of the parotid gland are characterized by a low five-year survival rate.
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