Hepatocellular cancer (HCC) occurs in the setting of chronic hepatitis B infection and cirrhosis of the liver. Most patients may already have a liver disease, hence the onset of HCC may be missed until it reaches an advanced stage. This article will review the presentation, diagnosis and treatment modalities of this disease.
OD Heslop, MF Smikle, NA Christian, KM Harvey, IE Vickers, JP Figueroa, SE Brown, CDC Christie, B Bain, EN Barton
Molecular analysis of 53 strains of human immunodeficiency virus type-1(HIV-1) from Jamaican patients revealed the presence of several subtypes and a high genetic diversity of the virus in Jamaica.
J Harriott, L Christie, S Wynter, V DaCosta, H Fletcher, M Reid
Rectal misoprostol in appropriately selected patients results in comparable blood loss at delivery as compared to standard therapy and may be a reasonable alternative for the active management of the third stage of labour in patients delivered outside of a hospital setting.
LM Pinto Pereira, S Boodoo, KA Dindial, A Hosein, TAR Seemungal, I Bekele
Patients over-estimate asthma control. Approximately 80% of patients attending specialist care in Trinidad have uncontrolled asthma. The Asthma Control Test and the Royal College of Physicians ‘three questions test’ evaluated disease control comparably. Formal evaluation of asthma control is recommended.
MK Tulloch-Reid, MS Boyne, MF Smikle, EG Choo-Kang, RH Parkes, RA Wright-Pascoe, EN Barton, RJ Wilks, DE Williams
In this study, there was a high prevalence of cardiovascular risk factors in the patients studied regardless of their diabetes type. While patients with Type 2 diabetes mellitus were more obese and had higher blood pressure readings when compared with those with Type1 diabetes, their overall glucose control was better. Differences in lipid profile were no longer significant after adjusting for BMI.
Cutaneous drug eruptions constitute a significant percentage of the patients referred for admission to a dermatology ward. This study was done to determine the causative drugs and consequences.
Congenital urological pathology is the commonest cause of chronic renal failure (CRF) in Jamaican children. Non-Urological disease often presents too late for corrective intervention, mortality is high because of limited access to dialysis. Paediatric dialysis/transplantation services are needed.
F Gayle, AK Soyibo, DT Gilbert, J Manzanares, EN Barton
Overall quality of life in patients with end stage renal disease is good. Domain of highest concern were burden of kidney disease and patient satisfaction.
HM Fletcher, G Wharfe, NP Williams, M Pedican, A Brooks, P Scott, G Gordon-Strachan
Venous thromboembolism is a serious complication of many conditions in women. It is more common in older hospitalized women, but should also be suspected in younger women who recently had surgery, hormonal therapy or pregnancy.
This report presenst results from the first study in the Caribbean to assess health- related quality of life in a young diabetic population using a diabetes specific quality of life scale (Diabetes-39).
R Alfred, O Okeke, C Moronu, V Elliot, A Frankson, EN Barton
The most common co-morbidities associated with acute myocardial infarction in Tobago are dyslipidaemia, hypertension and diabetes mellitus. End Stage Renal Failure, smoking and cocaine use follow closely behind.
WM West, N Younger, D Brady-West, DT Gilbert, G Char, EN Barton
A retrospective review was done of stroke subtypes seen on CT and MRI at the University Hospital of the West Indies during a three-year period. The most common stroketype was ischaemic infarct followed by intracerebral bleed.
For primary glomerular disease, focal and segmental glomerulosclerosis, minimal and membranous glomerulonephritis were the most frequent histological types.