The Caribbean is now recording the 2nd highest incidence of HIV/AIDS in the world, after sub-Saharan Africa. This article examines the rising incidence and prevalence of AIDS by country in the Caribbean, pointing out that Haiti and the Dominican Republic are the leading countries in terms of both numbers and rates. The article points out further that many factors including cultural practices, attitudes, norms and values, promiscuity and multiple sexual partners work together to determine the increasing incidence of AIDS in the Caribbean. Other contributing factors include the cultural attitudes towards homosexuality and the lack of laws protecting homosexuality and prostitution as well as the lack of adequate information on the rising incidence of the diseases in many countries.