Objective: Haemophilia is a congenital bleeding disorder characterized by partial or complete deficiency of a clotting factor VIII (FVIII) for Haemophilia A (HA), or factor IX (FIX) for Haemophilia B (HB). In this study, we describe the epidemiology of haemophilia in patients from Martinique, a French Caribbean Island with a population of predominantly Afro-Caribbean origin. This epidemiological study has never been described before, and the associated specific mutations for the corresponding genes were unknown.