Cytochrome c oxidase catalyses the reduction of oxygen to water at two vastly different rates determined by the prevailing conformation. We employed bio-computing to view the enzyme’s oxygen/ligand binding site but found no evidence that this site cycles between an opened and closed position as predicted by others.

There is no comparative study in the literature regarding Demodex folliculorum prevalence in rosacea (RSC) and seborrhoeic dermatitis (SD) using standardized skin surface biopsy. Our study showed that D folliculorum prevalance in RSC was three times higher than SD, and D folliculorum may play a more important role in the aetiopathogenesis of RSC than SD.