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Pityriasis lichenoides chronica Associated with Use of HMG-CoA Reductase Inhibitors

Journal Authors: 
Issue: 
DOI: 
Doi:10.7727/wimj.2011.023
Pages: 
743–5

ABSTRACT

Herein, we present three cases of Pityriasis lichenoides chronica (PLC) in patients who developed the rash after use of 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase inhibitors. The patients had complete resolution after standard treatment by dermatologists and withdrawal of the offending agents. In one case, the patient had a previous episode of a similar rash that occurred with HMG-CoA reductase inhibitors use many years previously. Pityriasis lichenoides chronica is a condition of unknown aetiology. Several agents have been associated with its presentation. We postulate HMG-CoA reductase inhibition in skin presents a final common pathway for the presentation of PLC in select patients.

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e-Published: 01 Mar, 2013
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