Aim: To discuss cerebral sinovenous thrombosis (CSVT), which is an important mortality and morbidity factor developing in progression of ulcerative colitis (UC) in childhood age, in the light of literature.
Materials and Methods: A review has been performed on database of Pubmed and Google Scholar Search on April 2014. The study retrospectively investigated the cases diagnosed UC with complication of CSVT below 18 years of age between years 1971 to 2014. The cases were analysed with respect to age, gender, disease duration and treatment, potential risk factors, clinical findings, location of thrombosis, thrombolytic therapeutical applications and clinical progressions.
Results: Twenty four paediatric cases aged between five and 18 years were included in the study. Cerebral sinovenous thrombosis had developed during active disease period in 23 (95.8%) periods. The most common application rationales were headache (79.1%) and emesis (29.1%). The most frequently detected risk factors for CSVT were anaemia (58.3%) and thrombocytosis (45.8%). Inherited thrombotic disorders were encountered 10 (41.6%) cases. The most common location sites for CSVT were transverse (33.3%) and sigmoid (33.3%) sinuses. It has been encountered that 19 (79.2%) cases were healed completely without a sequela whereas neurological sequelae remained in 3 (12.5%) cases and 2 (8.3%) cases died.
Conclusion: When a paediatric patient diagnosed with UC within apply emergency service with emesis, headache and mood changes during especially seizure; presence of CSVT should be certainly considered.
Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.