In this study, we investigated the risk factors, clinical and laboratory findings, treatment and prognosis of cerebral sinovenous thrombosis (CSVT)—an important contributor to morbidity and mortality, associated with the progression of ulcerative colitis (UC) during childhood. The study inferred that CSVT should be considered in paediatric patients with a prior diagnosis of UC and presenting with symptoms of emesis, headache, and mood changes and particularly seizures.