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Recurrent Priapism Related with Low Single Dose Olanzapine



Priapism is defined as persistent prolonged erection of the penis, usually painful, without sexual arousal or desire, generally continuing for hours. Many medical situations and drugs, especially psychotropic agents, may cause priapism. The mechanism of psychotropic drug-induced priapism is not fully known, but α1- adrenergic receptor blockade in the corpus cavernous is being accused. Priapism is an urgent situation for the health of the patient. Cavernous old blood is drained by a butterfly needle or a diluted solution of an alpha-adrenergic agonist is injected into the corporal space. In the event failure of medical treatment, surgical interference may be needed to avert fibrosis and impotence due to tissue death. For preventing that condition, a fistula between the deep dorsal vein or saphenous vein and the glans penis, the corpus cavernosum, and corpus spongiosum is constituted to open a new way for the venous circulation.

02 Feb, 2016
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e-Published: 01 Mar, 2016


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