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Zhenju Jiangya Tablet-induced Acute Kidney Injury: A Case Report and Literature Review



Zhenju Jiangya tablet is used to control hypertension, and it is composed by traditional Chinese medicines. Weight of each piece is 0.26g. It is dangerous for patients allergic to hydrochlorothiazide, clonidine and sulfa drugs; it is also banned from pregnant women, lactating women. There is no adverse reaction in most patient who accept the Zhenju Jiangya tablet, and few patients has following symptoms: dry mouth, polyuria, fatigue. After application with Zhenju Jiangya tablet, the worst adverse reactions are photosensitivity dermatitis, drug eruption, electrolyte balance disorders and acute gouty arthritis. There are reports cases on elevated blood glucose, but no reports on acute kidney injury (AKI). We reported an episode of AKI associated with Zhenju Jiangya tablet use and discussed this topic in medical literature. Zhenju Jiangya tablet-induced AKI is rare. The mechanism and pathogenesis of Zhenju Jiangya tablet-induced AKI remains unknown. The aim of the present report is to remind most of the medical workers, especially the grassroots medical workers to concern about this drug and the disease.

09 Oct, 2015
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e-Published: 21 Mar, 2016


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