INTRODUCTION

ABSTRACT

Pharmacovigilance supports safe and appropriate use of drugs. Spontaneous reporting of adverse drug reactions (ADRs) is an essential component of pharmacovigilance. However, there is significant underreporting of ADRs. Adverse drug reactions have become a major problem in developing countries. Knowledge of pharmacovigilance could form the basis for interventions aimed at improving reporting rates and decreasing ADRs.

ABSTRACT

DRESS syndrome (drug reaction with eosinophilia and systemic symptoms), previously named ‘’drug hypersensitivity syndrome’’, is a severe adverse drug reaction characterized by skin rash, fever, lymph node enlargement and internal organ involvement. We report on a 7-year old girl who developed DRESS syndrome caused by penicillin V treatment.

Etofenamate is a non-steroidal anti-inflammatory drug (NSAID). Clinical findings caused by etofenamate
are uncommon. Allergic contact dermatitis is the most common cutaneous reaction reported. But
petechial eruption due to etofenamate had not been reported yet. This report concerns an 11-year old
male with petechial eruption after application of topical etofenamate.
Physicians need to be aware that patients can develop an asymptomatic purpuric eruption when
etofenamate is ordered.

Etofenamate is a non-steroidal anti-inflammatory drug (NSAID). Clinical findings caused by etofenamate are uncommon. Allergic contact dermatitis is the most common cutaneous reaction reported. But petechial eruption due to etofenamate had not been reported yet. This report concerns an 11-year old male with petechial eruption after application of topical etofenamate.
Physicians need to be aware that patients can develop an asymptomatic purpuric eruption when etofenamate is ordered.