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Health-related Quality of Life and Risk of Malnutrition among Persons on Maintenance Haemodialysis

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Objectives: The purpose of this study was to determine health-related quality of life (HRQOL) and risk of malnutrition among persons with chronic kidney disease (CKD), on maintenance haemodialysis.

Methods: A mixed-method approach consisting of a case-control study followed by detail interviews was employed. Cases had three haemodialysis sessions per week. Controls were persons diagnosed with hypertension and or diabetes mellitus attending clinics at the same healthcare facility.Face-to-face interviews were conducted using a standardized questionnaire consisting of the SF-12 and mini nutritional assessment questionnaire as well as sociodemographic, health-related symptoms, food frequency and physical activity. Anthropometry was assessed using standard procedures. Sixty participants completed the questionnaires on two occasions, eight weeks apart. The study was approved by The University of the West Indies Ethics Committee.

Results: Four hundred and seventy-three persons (cases = 150; controls = 323) participated in the study. Among female haemodialysis participants Cronbach alpha for physical component scores were 0.68 and 0.75 for mental component scores. Among male haemodialysis participants Cronbach alpha were 0.5 for mental component scores and 0.53 for physical component scores. There were no significant differences in the age, body mass index and genders between cases and controls. Cases were more likely than controls to be at increased risk for poorer HRQOL and malnutrition. Malnutrition scores were positively associated with physical component scores (p = 0.025) and mental component scores (p = 0.002)

Conclusion: Cases had poorer health-related quality-of-life and were at higher-risk of malnutrition than controls.


21 Jan, 2019
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e-Published: 08 Mar, 2019


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