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Sustained Increase of Serum Creatine Phosphokinase Levels and Progressive Muscle Abnormalities Associated with Raltegravir Use during 32-week Follow-up in an HIV-1 Experienced Patient on Simplified HAART Regimen, Intolerant to PIs and Abacavir: A Case Rep

10.7727/wimj. 2011.193


Sustained increase of serum creatine phosphokinase (CPK) concentrations and muscle abnormalities have been reported in patients taking raltegravir (RAL). In this report, we describe a case of sustained and asymptomatic increase of serum CPK concentrations associated with raltegravir, zidovudine, and lamivudine in an HIV-1 experienced patient with intolerance to protease inhibitor, abacavir and pencillin during 32 weeks of continuous drug monitoring.

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e-Published: 14 Aug, 2013
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