In pregnant patients with polycystic ovary syndrome, continuing metformin until 8-12 weeks gestation seems to be effective in preventing miscarriage without proven teratogenic effects.
ABSTRACT
Background: This study was performed with the aim of evaluating the effect of metformin in reducing miscarriage when continued until the end of the first trimester of pregnancy in patients with polycystic ovary syndrome (PCOS) and infertility.