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P Almirall

A Randomized, Controlled, Open-label Trial Evaluating the Efficacy and Safety of Chloroquine in the Treatment of Giardiasis in Children

This randomized clinical trial evaluated the efficacy and safety of two drugs in the treatment of Giardia lamblia infection in Cuban children. The authors demonstrated that chloroquine, for five days, was as efficacious as metronidazole in treating Giardia lamblia.


Background: Giardia duodenalis is among the commonest protozoan parasites in the intestinal tract of humans and may cause significant morbidity worldwide. Although there are several antigiardial agents, treatment failures have been commonly reported.

Objective: To compare the efficacy and safety of chloroquine (CQ) versus metronidazole (MTZ) in the treatment of children with confirmed G duodenalis mono-infection.

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e-Published: 15 Oct, 2013
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