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Dietary supplements

Effects of Melatonin Suplementation in Human Pathologie: A Systematic Review

Melatonin is a hormone primarily produced in the pineal gland. Its most important functions are the regulation of circadian sleep-wake cycle, anti-inflammatory and antioxidant. Therefore, it use as a dietary supplement could have implications for clinical practice.


Objectives: to analyse the main effects of melatonin dietary supplementation in different pathologies.

Method: systematic review related to the use of melatonin as a dietary supplement and its effects on PubMed, CINAHL, Scopus, ProQuest Health and Medical Complete, Scielo and Dialnet databases.

11 Jan, 2017
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e-Published: 01 Feb, 2017


Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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