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Multiplex Polymerase Chain Reaction

Molecular Detection and Epidemiology of Extended-Spectrum Beta-lactamase Genes Prevalent in Clinical Isolates of Klebsiella pneumoniae and E coli from Trinidad and Tobago

Issue: 
Pages: 
591–6
Synopsis: 
This first report of molecular characterization and epidemiology of ESBL subtypes in E coli and K pneumoniae isolates in Trinidad and Tobago shows that the CTX-M, mainly phylogenetically group 1 type, was most predominant. Most ESBL producing isolates were still susceptible to carbapenems and aminoglycosides and their spread appears to be polyclonal and clonally unrelated.

ABSTRACT


Objective: The epidemiology of Extended-spectrum beta-lactamase (ESBL) producing E coli and K pneumoniae is complex and varies among hospitals and countries. This study aimed at describing the molecular detection and epidemiology of ESBL subtypes prevalent in clinical isolates of K pneumonia and E coli in Trinidad and Tobago.

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e-Published: 15 Oct, 2013
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