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Endothelial Dysfunction in Primary Sjögren Syndrome



Objective: In this study, we aimed to investigate endothelial functions in primary Sjögren syndrome.
Methods: Thirty-five patients with primary Sjögren syndrome and 20 age and sex-matched healthy volunteers were recruited to the present study. Flow mediated dilatation of brachial artery and carotid intima-media thickness were measured in the study population.
Results: Carotid intima-media thickness values were similar between groups (0.50 ± 0.10, 0.053 ± 0.08, p > 0.05). Flow mediated dilatation of the brachial artery was disrupted in the primary Sjögren syndrome group (7% vs 12%, p = 0.002).
Conclusion: There is endothelial dysfunction in patients with primary Sjögren syndrome, although they had comparable carotid intima-media thickness with the healthy control group.

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e-Published: 20 Feb, 2013

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