ABSTRACT
Background: The clinical characteristics of patients who had lymph node-negative early breast cancer were assessed.
Methods: We assessed a total of 579 patients in the study, including 74 patients (12.8%) with T1a, 119 patients (20.7%) and 367 patients (63.7%) with T1c. Patients with T1 tumors were further classified into 3 groups according to hormone receptor (HR) and HER-2 status.
Results: In patients with T1a, the disease-free survival (DFS) rate was 98.4% at 2 years (p=0.000). In subgroup analysis of early breast cancers, 10-year-DFS rates of the patients in HR (+)/HER2 (-), HR (-) /HER2 (+) and HR (-)/HER2 (-) subgroups were no significant difference (p = 0.917).
Conclusion: The T1a group had a worse prognosis than T1b and T1c groups in second years (p=0.000), but there was no statistically important difference between subgroups (p=0.917). Although there are differences in patients and tumor features, the prognosis of patients with T1a, b, cN0M0 breast cancer is excellent.
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