ABSTRACT
Objective: This study was aimed to investigate the protective effect of hydrogen on cigarette smoke-induced damage in rat reproductive system.
Methods: Adult male rats which suffered smoke were randomly divided into four groups, then total sperm count was counted, testosterone, superoxide dismutase (SOD), malondialdehyde (MDA) of serum and testis were determined. H&E straining of the testis tissues was also performed.
Results: Our results showed that rats in SK+HSI group (passive smoking and hydrogen injection group) exhibited larger amount of sperm count, smaller sperm deformation rate, higher levels of testosterone and SOD in serum and testis, lower levels of MDA in testis and less morphologic abnormalities compared to SK+NSI group (passive smoking and nitrogen injection group).
Conclusion: We concluded that hydrogen injected exerted protective effects on rats’ reproductive system exposed to cigarette smoke through inhibiting oxidative damage.
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