Although cow’s milk protein is one of the most common food allergens in infancy, there are few reports about cow's milk allergy (CMA) in neonates (1). The symptoms due to CMA can be occured from birth, though in exclusively breast-fed newborns (2). While gastrointestinal symptoms are seen commonly, cutaneous symptoms are extremely rare in neonatal period (3). Here, we report a newborn who developed urticaria due to cow’s milk, as it is seen rarely in neonatal period.
A 24-day-old female infant was admitted to neonatal unit with a general urticarial rash for two days. There was no family history of atopia. The baby was exclusively breast-fed since birth. On the physical examination, a generalized urticarial rash was noted over the trunk, face and limbs. Erythematous plaques arised a central swelling and central pallor which typically disappeared without residual lesion (Figure 1 and 2).
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