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G LaPointe

Comparative Antimicrobial Activity of Two New Mutacins

The comparative in vitro activity of two bacteriocins produced by Streptococcus mutans is presented. Results show that these mutacins are active against pathogens including antibiotic-resistant bacteria. Based on their activity spectra, potential applications are proposed for each bacteriocin.


Objectives: To compare the in vitro activity of mutacins D-123.1 and F-59.1 against different bacteria including antibiotic-resistant strains, in order to evaluate their application potential.

Design and Methods: The antibacterial activity spectrum of purified F-59.1 and the MIC and MBC of F-59.1 and D-123.1 against target bacteria were determined.

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e-Published: 15 Oct, 2013
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